Problem Set 18 Predict the major organic products of the following reactions : 1 ) LDA 2 ) – Br 8 ) 2 i NaOH H20 2 ) 2 Na OCH3 + CH3OH NaOCH3 , CH3OH…

Please propose mechanisms to as many reactions as you can,( we haven’t covered it yet in class, and unfortunately covering this whole chapter the day before our cumulative final exam! so I would like to at least understand some of it. Thank you so much for all your help !

Problem Set 18Predict the major organic products of the following reactions :1 ) LDA2 )- Br8 ) 2 iNaOHH202 ) 2Na OCH3 +CH3OHNaOCH3 , CH3OH-H3) 2JHNaOHH20NaOHPh10) 2 Ph HH 20Ph(4 ). H+PhLHNaOH-HH 201 )- OCH3OCHsNOOCH3 , CH3OHHOCHS5 )1 ) NaOCH32 ) CH3 I6 ) 2- OCH 3NaOCH3 ,OCH3CH3OH* Aldol reactions should be studied in the forward andreverse direction ( retrosynthesis ). Make sure you can go7 ) 2NaOCH 2 CH 3OCH 2 CH3 CH3 CH 2OH* KOCH 2 CH3from the aldol product back to the starting materialsby making the right bond disconnections.

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