Need help with my writing homework on The Laboratory Development of Cardiac Markers Used In the Investigations of Patients with Suspected Acute Myocardial Infarction. Write a 1250 word paper answering; Focusing on the above aspects, the essay discusses the laboratory development of cardiac markers used for investigating patients with suspected AMI. The study further extrapolates the development of atherosclerosis. Apart from this, the essay also explains the effectiveness of protein as well as enzyme markers with respect to sensitivity along with specificity which is used to identify myocardial infarction.
Mechanisms Involved In the Development of Atherosclerosis
Clinical event that emerges from the atherosclerosis is directly related with the oxidation of the lipids in ‘Low-density Lipoprotein’ (LDL). LDLs are considered as a key part of progression of atherosclerosis. On the basis of the study of Rovere &. et. al. (2013), it can be observed that LDLs are confined in the extracellular matrix of the sub-endothelial space which generates ‘fatty streak’, the first tissue that triggers the development of atherosclerosis. Traditionally, atherosclerosis was thought to be a degenerative disease, resulting from aging. However, with the advancement in medical science, it has been discovered that atherosclerosis is a chronic inflammatory condition which is further converted into acute clinical occurrence by induction of plaque rupture, a collection of lipids. Plague rapture leads to thrombosis, which plays a critical role in the creation of fatty streak, hence atherosclerosis (Berliner &. et. al., 2013).
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